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- CAS Number: 331-25-9
- Stock: 428g
- Assay: 98.00%
Sotorasib (2296729-00-3), Stock 281g, World biggest supplier.
Sotorasib (2296729-00-3), HPLC 98.75%, HNMR, MASS, HPLC, COA, MSDS we supply.
Sotorasib (2296729-00-3), batch size 1kg, White powder.
AMG-510 racemate, is a racemic mixture of AMB-510, which is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRAS p.G12C mutant, at either the DNA, RNA or protein level, and prevents, through an as of yet not elucidated manner, expression of and/or tumor cell signaling through the KRAS p.G12C mutant. This may inhibit growth in KRAS p.G12C-expressing tumor cells. Note: According to Sci-Finder database, CAS#2252403-56-6 is a AMG510 active atropisomer. Many vendor mistakenly listed CAS#2296729-00-3 as the AMG510 active atropisomer.
Name: AMG-510 racemate
CAS#: 2296729-00-3 (racemate)
Chemical Formula: C30H30F2N6O3
Exact Mass: 560.2347
Molecular Weight: 560.6058
Elemental Analysis: C, 64.28; H, 5.39; F, 6.78; N, 14.99; O, 8.56
Synonym: AMG-510 racemate; AMG 510; AMG-510; AMG510; Sotorasib;
IUPAC/Chemical Name: 4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
InChi Key: NXQKSXLFSAEQCZ-SFHVURJKSA-N
InChi Code: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
SMILES Code: O=C1N(C2=C(C)C=CN=C2C(C)C)C3=NC(C4=C(O)C=CC=C4F)=C(F)C=C3C(N5[C@@H](C)CN(C(C=C)=O)CC5)=N1
Appearance: Whie powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001