CAS 97534-21-9: Merbarone
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Merbarone, CAS 97534-21-9

Merbarone, CAS 97534-21-9, Stock 423g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of Merbarone.

Merbarone

Merbarone, also known as NSC-336628; RLBN-1001, is a Type II DNA topoisomerase inhibitor potentially for the treatment of solid tumors. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix. Merbarone induces apoptosis in CEM cells through activation of ICE/CED-3-like protease. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage.

Product Details:

Name: Merbarone

CAS#: 97534-21-9

Chemical Formula: C11H9N3O3S

Exact Mass: 263.0365

Molecular Weight: 263.271

Elemental Analysis: C, 50.18; H, 3.45; N, 15.96; O, 18.23; S, 12.18

Specification:

Synonym: Merbarone; NSC-336628; RLBN-1001; NSC336628; RLBN1001.

IUPAC/Chemical Name: 5-(N-Phenylcarboxamido)-2-thiobarbituric acid

InChi Key: KIHGHKYNPNVMLM-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H9N3O3S/c15-6-14(7-4-2-1-3-5-7)8-9(16)12-11(18)13-10(8)17/h1-6,8H,(H2,12,13,16,17,18)

SMILES Code: S=C(NC(C1N(C2=CC=CC=C2)C=O)=O)NC1=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: