CAS 956958-53-5 : XL147-II
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XL147-II, CAS 956958-53-5

XL147-II, CAS 956958-53-5, Stock 234g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of XL147-II.

XL147-II

XL147-II is an ATP-competitive inhibitor of class I PI3K isoforms. It acts by abrogating Akt and S6 phosphorylation in HER2+ cells and also inducing the expression and phosphorylation of HER3 and other RTKs.

Product Details:

Name: XL147-II

CAS#: 956958-53-5

Chemical Formula: C21H16N6O2S2

Exact Mass: 448.0776

Molecular Weight: 448.51

Elemental Analysis: C, 56.24; H, 3.60; N, 18.74; O, 7.13; S, 14.30

Specification:

Synonym: XL147-II; XL147 II; XL147II; XL147 derivative II; XL147derivativeII; XL147-derivative-II;

IUPAC/Chemical Name: N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-benzenesulfonamide

InChi Key: MQMKRQLTIWPEDM-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H16N6O2S2/c1-13-6-9-15(10-7-13)31(28,29)27-21-20(23-16-4-2-3-5-17(16)24-21)22-14-8-11-18-19(12-14)26-30-25-18/h2-12H,1H3,(H,22,23)(H,24,27)

SMILES Code: O=S(C1=CC=C(C)C=C1)(NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: