CAS 897016-26-1: KX2-361
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- CAS Number: 897016-26-1
- Stock: 268g
- Assay: 99.20%
KX2-361，CAS 897016-26-1， Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of KX2-361.
KX02, also known as KX2-361, is a lipophilic, orally available inhibitor of both Src kinase activity and tubulin polymerization, with potential antineoplastic activity. Upon oral administration, src/tubulin inhibitor KX02 binds to and inhibits the activity of Src kinase. This inhibits both downstream signaling and the proliferation of Src kinase-expressing tumor cells. KX02 also binds to tubulin heterodimers and inhibits microtubule polymerization, thereby disrupting microtubule formation, mitosis, and further proliferation.
Chemical Formula: C24H24FN3O2
Exact Mass: 405.1853
Molecular Weight: 405.4734
Elemental Analysis: C, 71.09; H, 5.97; F, 4.69; N, 10.36; O, 7.89
Synonym: KX 2-361; KX2-361; KX-2-361; KX 2361; KX2361; KX-2361; KX 2361; KX 02; KX02; KX-02
IUPAC/Chemical Name: N-(3-fluorobenzyl)-2-(5-(4-morpholinophenyl)pyridin-2-yl)acetamide
InChi Key: CMKKPJNMYLOUCE-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H24FN3O2/c25-21-3-1-2-18(14-21)16-27-24(29)15-22-7-4-20(17-26-22)19-5-8-23(9-6-19)28-10-12-30-13-11-28/h1-9,14,17H,10-13,15-16H2,(H,27,29)
SMILES Code: O=C(NCC1=CC=CC(F)=C1)CC2=NC=C(C3=CC=C(N4CCOCC4)C=C3)C=C2
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001