CAS 894787-30-5: ST2825

CAS 894787-30-5: ST2825
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  • CAS Number: 894787-30-5
  • Stock: 268g
  • Assay: 99.20%

ST2825

ST2825, CAS 894787-30-5, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of ST2825.


ST2825

ST-2825 is MyD88 inhibitor. ST2825 provides neuroprotection after experimental traumatic brain injury in mice. ST2825 significantly inhibited the proliferation of and promoted the apoptosis of HCC cells. Moreover, ST2825 significantly decreased bcl-2 expression, increased cleaved caspase-3 expression (P < 0.05), and reduced p65 nuclear expression (P < 0.05) in a dose-dependent manner. ST2825 inhibits the proliferation of and promotes the apoptosis of HCC cells, thereby suggesting that ST2825 may be a new drug for HCC treatment.


Product Details:

Name: ST2825

CAS#: 894787-30-5

Chemical Formula: C27H28Cl2N4O5S

Exact Mass: 590.1157

Molecular Weight: 591.504

Elemental Analysis: C, 54.83; H, 4.77; Cl, 11.99; N, 9.47; O, 13.52; S, 5.42


Specification:

Synonym: ST-2825; ST 2825; ST2825.

IUPAC/Chemical Name: (2R,4'R,8a'R)-1-(2-(4-(2-(2,4-dichlorophenoxy)acetamido)phenyl)acetyl)-6'-oxotetrahydro-2'H,6'H-spiro[pyrrolidine-2,7'-pyrrolo[2,1-b][1,3]thiazine]-4'-carboxamide

InChi Key: HBLHLJXFIPCEMW-ZJSFPPFMSA-N

InChi Code: InChI=1S/C27H28Cl2N4O5S/c28-17-4-7-21(19(29)13-17)38-15-22(34)31-18-5-2-16(3-6-18)12-23(35)32-10-1-9-27(32)14-24-33(26(27)37)20(25(30)36)8-11-39-24/h2-7,13,20,24H,1,8-12,14-15H2,(H2,30,36)(H,31,34)/t20-,24-,27-/m1/s1

SMILES Code: O=C([C@@H]1N2[C@](C[C@@]3(N(C(CC4=CC=C(NC(COC5=CC=C(Cl)C=C5Cl)=O)C=C4)=O)CCC3)C2=O)([H])SCC1)N

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: