CAS 890190-22-4: WDR5-0103
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- CAS Number: 890190-22-4
- Stock: 268g
- Assay: 99.20%
WDR5-0103
WDR5-0103, CAS 890190-22-4, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of WDR5-0103.
WDR5-0103
WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC50 = 39 µM). WD repeat domain 5 (WDR5) plays an important role in various biological functions through the epigenetic regulation of gene transcription. WDR5 may have oncogenic effect and WDR5-mediated H3K4 methylation plays an important role in leukemogenesis.
Product Details:
Name: WDR5-0103
CAS#: 890190-22-4
Chemical Formula: C21H25N3O4
Exact Mass: 383.1845
Molecular Weight: 383.448
Elemental Analysis: C, 65.78; H, 6.57; N, 10.96; O, 16.69
Specification:
Synonym: WDR5-0103; WDR 5-0103; WDR-5-0103; WDR50103; WDR-50103; WDR 50103; WD-Repeat Protein 5-0103.
IUPAC/Chemical Name: methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate
InChi Key: ZPLBXOVTSNRBFB-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H25N3O4/c1-23-9-11-24(12-10-23)19-8-7-16(21(26)28-3)14-18(19)22-20(25)15-5-4-6-17(13-15)27-2/h4-8,13-14H,9-12H2,1-3H3,(H,22,25)
SMILES Code: O=C(OC)C1=CC(NC(C2=CC=CC(OC)=C2)=O)=C(N3CCN(C)CC3)C=C1
Appearance: White to beige solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
