CAS 890128-81-1: BFH772
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- CAS Number: 890128-81-1
- Stock: 268g
- Assay: 99.20%
BFH772
BFH772, CAS 890128-81-1, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of BFH772.
BFH772
BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.
Product Details:
Name: BFH772
CAS#: 890128-81-1
Chemical Formula: C23H16F3N3O3
Exact Mass: 439.1144
Molecular Weight: 439.39
Elemental Analysis: 62.87; H, 3.67; F, 12.97; N, 9.56; O, 10.92
Specification:
Synonym: BFH-772; BFH 772; BFH772.
IUPAC/Chemical Name: 6-((6-(hydroxymethyl)pyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide
InChi Key: JNLSTLQFDDAULK-UHFFFAOYSA-N
InChi Code: InChI=1S/C23H16F3N3O3/c24-23(25,26)15-4-2-5-16(10-15)29-22(31)20-6-1-3-14-9-18(7-8-19(14)20)32-21-11-17(12-30)27-13-28-21/h1-11,13,30H,12H2,(H,29,31)
SMILES Code: O=C(C1=C2C=CC(OC3=NC=NC(CO)=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
