15830249 CAS 853400-76-7: Trofinetide

CAS 853400-76-7: Trofinetide

  • CAS 853400-76-7: Trofinetide

CAS 853400-76-7: Trofinetide
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  • CAS Number: 853400-76-7
  • Stock: 270g
  • Assay: 99.70%

CAS 853400-76-7: Trofinetide

CAS 853400-76-7: Trofinetide, Stock 270g, Assay 99.7%, White powder, Water 0.27%.

Trofinetide

Trofinetide, also known as NNZ-2566, is a glypromate (or Gly-Pro-Glu) analog and neuroprotectant. NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury. NNZ-2566 demonstrates neuroprotective efficacy in models of traumatic brain injury. NNZ-2566 significantly decreases injury-induced upregulation of inflammatory cytokines including TNF-α, IFN-γ, and IL-6. NNZ-2566 is a potential therapeutic agent for fragile X syndrome.


Product Details:

Name: Trofinetide

CAS#: 853400-76-7

Chemical Formula: C13H21N3O6

Exact Mass: 315.14

Molecular Weight: 315.326

Elemental Analysis: C, 49.52; H, 6.71; N, 13.33; O, 30.44


Specification:

Synonym: NNZ-2566; NNZ 2566; NNZ2566; Trofinetide

IUPAC/Chemical Name: ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid

InChi Key: BUSXWGRAOZQTEY-SDBXPKJASA-N

InChi Code: InChI=1S/C13H21N3O6/c1-13(5-2-6-16(13)9(17)7-14)12(22)15-8(11(20)21)3-4-10(18)19/h8H,2-7,14H2,1H3,(H,15,22)(H,18,19)(H,20,21)/t8-,13-/m0/s1

SMILES Code: O=C(O)CC[C@@H](C(O)=O)NC([C@@]1(C)N(C(CN)=O)CCC1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001