CAS 817194-38-0: GSK180736A
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GSK180736A, CAS 817194-38-0

GSK180736A, CAS 817194-38-0, Stock 423g, Assay 99.34%, White powder, EOS Med Chem is big manufacturer of GSK180736A.

GSK180736A

GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 μM25 and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA with an IC50 of 30 μM, but highly potent against ROCK1 (IC50 = 100 nM).

Product Details:

Name: GSK180736A

CAS#: 817194-38-0

Chemical Formula: C19H16FN5O2

Exact Mass: 365.1288

Molecular Weight: 365.3684

Elemental Analysis: C, 62.46; H, 4.41; F, 5.20; N, 19.17; O, 8.76

Specification:

Synonym: GSK180736A; GSK-180736A; GSK 180736A.

IUPAC/Chemical Name: 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide

InChi Key: HEAIGWIZTYAQTC-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H16FN5O2/c1-10-16(17(24-19(27)22-10)11-2-4-13(20)5-3-11)18(26)23-14-6-7-15-12(8-14)9-21-25-15/h2-9,17H,1H3,(H,21,25)(H,23,26)(H2,22,24,27)

SMILES Code: CC1=C(C(NC(=O)N1)C2=CC=C(C=C2)F)C(=O)NC3=CC4=C(C=C3)NN=C4

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: