CAS 583037-91-6: EC-17 free acid
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CAS 583037-91-6: EC-17 free acid

CAS 583037-91-6: EC-17 free acid, Stock 400g, Assay 99.25%, Off-White powder, EOS Med Chem is big manufacturer of EC-17 free acid.

EC-17 free acid

EC17, also known as Folate-FITC, is an FITC conjugated folic acid. It also acts as a FRα-targeting agent that fluoresces at 500nm. EC17 is conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, curculating anti-fluorescein antibodies.may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity.

Product Details:

Name: EC-17 free acid

CAS#: 583037-91-6 (acid)

Chemical Formula: C42H36N10O10S

Exact Mass: 872.2337

Molecular Weight: 872.87

Elemental Analysis: C, 57.79; H, 4.16; N, 16.05; O, 18.33; S, 3.67

Specification:

Related CAS #: 910661-33-5 (sodium)   583037-91-6 (acid)    

Synonym: EC17; EC-17; EC 17; Folate-FTIC; FTIC-Folate;

IUPAC/Chemical Name: (S)-5-(3-(2-(4-(4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanamido)ethyl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid

InChi Key: GYVKRHIWZKXLDZ-PMERELPUSA-N

InChi Code: InChI=1S/C42H36N10O10S/c43-41-51-36-35(38(57)52-41)48-23(19-47-36)18-46-21-3-1-20(2-4-21)37(56)50-30(40(60)61)11-12-33(55)44-13-14-45-42(63)49-22-5-8-26(29(15-22)39(58)59)34-27-9-6-24(53)16-31(27)62-32-17-25(54)7-10-28(32)34/h1-10,15-17,19,30,46,53H,11-14,18H2,(H,44,55)(H,50,56)(H,58,59)(H,60,61)(H2,45,49,63)(H3,43,47,51,52,57)/t30-/m0/s1

SMILES Code: O=C(O)C1=CC(NC(NCCNC(CC[C@H](NC(C2=CC=C(NCC3=CN=C4NC(N)=NC(C4=N3)=O)C=C2)=O)C(O)=O)=O)=S)=CC=C1C5=C6C=CC(C=C6OC7=C5C=CC(O)=C7)=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: