CAS 553-21-9: Costunolide

CAS 553-21-9: Costunolide
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  • CAS Number: 553-21-9
  • Stock: 268g
  • Assay: 99.20%

Costunolide

Costunolide, CAS  553-21-9, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Costunolide.


Costunolide

Costunolide, also known as (+)-Costunolide, CCRIS 6754 and NSC 106404, is a naturally occurring sesquiterpene lactone, first isolated in Saussurea costus roots in 1960. It is also found in lettuce. Costunolide has been reported for the wide spectrum of biological effects, including anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal, antioxidant, antidiabetic, antiulcer, and anthelmintic activities. In recent years, it have caused extensive interest in researchers due to its potential anti-cancer activities for various types of cancer, and their anti-cancer mechanisms, including causing cell cycle arrest, inducing apoptosis and differentiation, promoting the aggregation of microtubule protein, inhibiting the activity of telomerase, inhibiting metastasis and invasion, reversing multidrug resistance, restraining angiogenesis has been studied.


Product Details:

Name: Costunolide

CAS#: 553-21-9

Chemical Formula: C15H20O2

Exact Mass: 232.1463

Molecular Weight: 232.323

Elemental Analysis: C, 77.55; H, 8.68; O, 13.77


Specification:

Synonym: CCRIS 6754; NSC 106404; Costunolide; Costus lactone; (+)-Costunolide

IUPAC/Chemical Name: (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one

InChi Key: HRYLQFBHBWLLLL-AHNJNIBGSA-N

InChi Code: InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1

SMILES Code: O=C(O[C@@]1([H])[C@@]2([H])CC/C(C)=C/CC/C(C)=C/1)C2=C

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: