CAS 552325-16-3 : A-443654
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- CAS Number: 552325-16-3
- Stock: 268g
- Assay: 99.20%
A-443654
A-443654, CAS 552325-16-3, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of A-443654.
A-443654
A-443654 is a potent and selective AKT inhibitor. A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition. A-443654 interferes with mitotic progression by regulating aurora a kinase expression.
Product Details:
Name: A-443654
CAS#: 552325-16-3
Chemical Formula: C24H23N5O
Exact Mass: 397.19026
Molecular Weight: 397.47
Elemental Analysis: C, 72.52; H, 5.83; N, 17.62; O, 4.03
Specification:
Synonym: A443564; A-443564; A 443564.
IUPAC/Chemical Name: (S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine
InChi Key: YWTBGJGMTBHQTM-IBGZPJMESA-N
InChi Code: InChI=1S/C24H23N5O/c1-15-22-10-16(6-7-24(22)29-28-15)17-9-20(13-26-11-17)30-14-19(25)8-18-12-27-23-5-3-2-4-21(18)23/h2-7,9-13,19,27H,8,14,25H2,1H3,(H,28,29)/t19-/m0/s1
SMILES Code: N[C@H](COC1=CC(C2=CC3=C(C)NN=C3C=C2)=CN=C1)CC4=CNC5=C4C=CC=C5
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001