CAS 552325-16-3 : A-443654

CAS 552325-16-3 : A-443654
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 552325-16-3
  • Stock: 268g
  • Assay: 99.20%

A-443654

A-443654, CAS 552325-16-3, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of A-443654.


A-443654

A-443654 is a potent and selective AKT inhibitor. A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition. A-443654 interferes with mitotic progression by regulating aurora a kinase expression.


Product Details:

Name: A-443654

CAS#: 552325-16-3

Chemical Formula: C24H23N5O

Exact Mass: 397.19026

Molecular Weight: 397.47

Elemental Analysis: C, 72.52; H, 5.83; N, 17.62; O, 4.03


Specification:

Synonym: A443564; A-443564; A 443564.

IUPAC/Chemical Name: (S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine

InChi Key: YWTBGJGMTBHQTM-IBGZPJMESA-N

InChi Code: InChI=1S/C24H23N5O/c1-15-22-10-16(6-7-24(22)29-28-15)17-9-20(13-26-11-17)30-14-19(25)8-18-12-27-23-5-3-2-4-21(18)23/h2-7,9-13,19,27H,8,14,25H2,1H3,(H,28,29)/t19-/m0/s1

SMILES Code: N[C@H](COC1=CC(C2=CC3=C(C)NN=C3C=C2)=CN=C1)CC4=CNC5=C4C=CC=C5

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: