CAS 547757-23-3 : BMS-345541 HCl

CAS 547757-23-3 : BMS-345541 HCl
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  • CAS Number: 547757-23-3
  • Stock: 268g
  • Assay: 99.20%

BMS-345541 HCl

BMS-345541 HCl, CAS 547757-23-3, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of BMS-345541 HCl.


BMS-345541 HCl

BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis.


Product Details:

Name: BMS-345541 HCl

CAS#: 547757-23-3 (HCl)

Chemical Formula: C14H18ClN5

Exact Mass: 291.12507

Molecular Weight: 291.78

Elemental Analysis: C, 57.63; H, 6.22; Cl, 12.15; N, 24.00


Specification:

Synonym: BMS 345541; BMS-345541; BMS345541; UNII-BXU277OCN5;

IUPAC/Chemical Name: 1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride

InChi Key: MIDKPVLYXNLFGZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H17N5.ClH/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15;/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18);1H

SMILES Code: NCCNC1=NC2=C(N3C1=NC=C3C)C=C(C)C=C2.[H]Cl

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: