CAS 541550-19-0: Apilimod free base

CAS 541550-19-0: Apilimod free base
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 541550-19-0
  • Stock: 268g
  • Assay: 99.20%

Apilimod free base, CAS 541550-19-0

Apilimod free base, CAS 541550-19-0, Stock 268g, Assay 99.20%, Off-white or White powder, EOS Med Chem is big manufacturer of Apilimod free base.


Apilimod free base

Apilimod, also known as STA-5326, is a IL-12/IL-23 inhibitor. Apilimod inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases - through the prevention of nuclear translocation of c-Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL-12 and IL-23 production by the drug.


Product Details:

Name: Apilimod free base

CAS#: 541550-19-0 (free base)

Chemical Formula: C23H26N6O2

Exact Mass: 418.2117

Molecular Weight: 418.501

Elemental Analysis: C, 66.01; H, 6.26; N, 20.08; O, 7.65


Specification:

Synonym: STA-5326; STA5326; STA 5326; LAM-002; LAM 002; LAM002; Apilimod free base.

IUPAC/Chemical Name: (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholin

InChi Key: HSKAZIJJKRAJAV-KOEQRZSOSA-N

InChi Code: InChI=1S/C23H26N6O2/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28)/b25-17+

SMILES Code: CC1=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=NC=CC=C4)=N2)=CC=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001



Certifications: