CAS: 2172870-89-0, Paltusotine
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- CAS Number: 2172870-89-0
- Stock: 210g
- Assay: 99.13%
Paltusotine, CAS: 2172870-89-0
Paltusotine, CAS: 2172870-89-0 Stock 210g, Assay 99.13%, White powder, EOS is one of TOP GMP manufacturer
Paltusotine
Paltusotine, also known as CRN00808, is a somatostatin receptor agonist. Paltusotine showed no direct inhibition of major cytochrome P450 enzymes or the hERG ion channel and had sufficient exposure in rats and excellent exposure in dogs upon oral dosing. In pharmacodynamic studies, Paltusotine dose-dependently suppressed growth hormone (GH) secretion induced by an exogenous growth-hormone-releasing hormone (GHRH) challenge in both male and female rats following a single oral dose and suppressed IGF-1 levels with repeated oral administration in both rats and dogs.
Product Details:
Name: Paltusotine free base
CAS#: 2172870-89-0 (free base)
Chemical Formula: C27H22F2N4O
Exact Mass: 456.1762
Molecular Weight: 456.4968
Elemental Analysis: C, 71.04; H, 4.86; F, 8.32; N, 12.27; O, 3.50
Specification:
Related CAS #: 2361216-83-1 (HCl); 2172870-89-0 (free base) 2172875-40-8 (2HCl)
Synonym: Paltusotine; CRN00808; CRN-00808; CRN 00808;
IUPAC/Chemical Name: 3-[4-(4-aminopiperidin-1-yl)-3-(3,5- difluorophenyl)quinolin-6-yl]-2-hydroxybenzonitrile
InChi Key: GHILNKWBALQPDP-UHFFFAOYSA-N
InChi Code: InChI=1S/C27H22F2N4O/c28-19-10-18(11-20(29)13-19)24-15-32-25-5-4-16(22-3-1-2-17(14-30)27(22)34)12-23(25)26(24)33-8-6-21(31)7-9-33/h1-5,10-13,15,21,34H,6-9,31H2
SMILES Code: N#CC1=CC=CC(C2=CC=C3N=CC(C4=CC(F)=CC(F)=C4)=C(N5CCC(N)CC5)C3=C2)=C1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Code: 2934.99.9001