CAS: 2172870-89-0, Paltusotine
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Paltusotine, CAS: 2172870-89-0

Paltusotine, CAS: 2172870-89-0 Stock 210g, Assay 99.13%, White powder, EOS is one of TOP GMP manufacturer

Paltusotine

Paltusotine, also known as CRN00808, is a somatostatin receptor agonist. Paltusotine showed no direct inhibition of major cytochrome P450 enzymes or the hERG ion channel and had sufficient exposure in rats and excellent exposure in dogs upon oral dosing. In pharmacodynamic studies, Paltusotine dose-dependently suppressed growth hormone (GH) secretion induced by an exogenous growth-hormone-releasing hormone (GHRH) challenge in both male and female rats following a single oral dose and suppressed IGF-1 levels with repeated oral administration in both rats and dogs.

Product Details:

Name: Paltusotine free base

CAS#: 2172870-89-0 (free base)

Chemical Formula: C27H22F2N4O

Exact Mass: 456.1762

Molecular Weight: 456.4968

Elemental Analysis: C, 71.04; H, 4.86; F, 8.32; N, 12.27; O, 3.50

Specification:

Related CAS #: 2361216-83-1 (HCl); 2172870-89-0 (free base)   2172875-40-8 (2HCl)    

Synonym: Paltusotine; CRN00808; CRN-00808; CRN 00808;

IUPAC/Chemical Name: 3-[4-(4-aminopiperidin-1-yl)-3-(3,5- difluorophenyl)quinolin-6-yl]-2-hydroxybenzonitrile

InChi Key: GHILNKWBALQPDP-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H22F2N4O/c28-19-10-18(11-20(29)13-19)24-15-32-25-5-4-16(22-3-1-2-17(14-30)27(22)34)12-23(25)26(24)33-8-6-21(31)7-9-33/h1-5,10-13,15,21,34H,6-9,31H2

SMILES Code: N#CC1=CC=CC(C2=CC=C3N=CC(C4=CC(F)=CC(F)=C4)=C(N5CCC(N)CC5)C3=C2)=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Code: 2934.99.9001

Certification: