CAS 210344-98-2: Z-IETD-FMK
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- CAS Number: 210344-98-2
- Stock: 411g
- Assay: 99.21%
Z-IETD-FMK, CAS 210344-98-2
Z-IETD-FMK, CAS 210344-98-2, Stock 411g, Assay 99.21%, White to off-white powder, EOS Med Chem is big manufacturer of Z-IETD-FMK.
Z-IETD-FMK
MDK4982, also known as Z-IETD-FMK, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B., The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. MDK4982 effectively inhibits influenza virus-induced apoptosis in HeLa cells. MDK4982 also inhibits granzyme B. MDK4982 has CAS#210344-98-2.
Product Details:
Name: Z-IETD-FMK
CAS#: 210344-98-2
Chemical Formula: C28H39FN4O11
Exact Mass: 626.2599
Molecular Weight: 626.6354
Elemental Analysis: C, 53.67; H, 6.27; F, 3.03; N, 8.94; O, 28.08
Specification:
Synonym: Z-IE(OMe)TD(OMe)-FMK; Granzyme B Inhibitor III; Z-IETD-FMK; MDK4982; MDK-4982; MDK 4982; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F.
IUPAC/Chemical Name: (5S,8S,11S,14S)-5-((S)-sec-butyl)-8-(2-carboxyethyl)-14-(2-fluoroacetyl)-11-((R)-1-hydroxyethyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oic acid
InChi Key: CTXDBLYOEUERAT-VUVYEONESA-N
InChi Code: InChI=1S/C28H39FN4O11/c1-4-15(2)23(33-28(43)44-14-17-8-6-5-7-9-17)26(41)30-18(10-11-21(36)37)25(40)32-24(16(3)34)27(42)31-19(12-22(38)39)20(35)13-29/h5-9,15-16,18-19,23-24,34H,4,10-14H2,1-3H3,(H,30,41)(H,31,42)(H,32,40)(H,33,43)(H,36,37)(H,38,39)/t15-,16+,18-,19-,23-,24-/m0/s1
SMILES Code: O=C(O)C[C@@H](C(CF)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC(OCC1=CC=CC=C1)=O)=O)=O)=O
Appearance: Solid powder
Purity: >99% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001