CAS 151767-02-1: Montelukast sodium
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Montelukast sodium, CAS 151767-02-1

Montelukast sodium, CAS 151767-02-1, Stock 223g, Assay 99.24%, Off-White powder, EOS Med Chem is big manufacturer of Montelukast sodium.

Montelukast sodium

Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.

Product Details:

Name: Montelukast sodium

CAS#: 151767-02-1 (sodium)

Chemical Formula: C35H35ClNNaO3S

Exact Mass: NA

Molecular Weight: 608.16877

Elemental Analysis: C, 69.12; H, 5.80; Cl, 5.83; N, 2.30; Na, 3.78; O, 7.89; S, 5.27

Specification:

Synonym: MK-476; MK476; MK 476; Montelukast sodium; trade names Singulair; Montelo-10; Monteflo; Lukotas; Lumona.

IUPAC/Chemical Name: sodium (R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetate

InChi Key: LBFBRXGCXUHRJY-HKHDRNBDSA-M

InChi Code: InChI=1S/C35H36ClNO3S.Na/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);/q;+1/p-1/b15-10+;/t32-;/m1./s1

SMILES Code: CC(C)(C1=CC=CC=C1CC[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)[O-])O.[Na+]

Appearance: White to off-white

Purity: >99.24% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in 1:9 EtOH:PBS (pH 7.2), EtOH, DMSO, and DMF

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO or water

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: