CAS 1268605-91-9: CTP-499

CAS 1268605-91-9: CTP-499
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  • CAS Number: 1268605-91-9
  • Stock: 561g
  • Assay: 99.23%

CTP-499, CAS 1268605-91-9

CTP-499, CAS 1268605-91-9, Stock 561g, Assay 99.23%, White powderWater 0.32%, Single Impurity 0.45%.


CTP-499

CTP-499 is a selective PDE inhibitor and deuterium-containing agent that slows the progression of type 2 diabetic kidney disease in patients with macroalbuminuria. CTP-499 is an HDX analog and a pentoxifylline metabolite. Initial testing showed that CTP-499 slowed the negative processes in diabetic kidney disease. Concert is developing the agent as a complementary treatment along with the standard of care, angiotensin modulation with an ACEi or ARB.


Product Details:

Name: CTP-499

CAS#: 1268605-91-9

Chemical Formula: C13H15D5N4O3

Exact Mass: 285.1849

Molecular Weight: 285.3585

Elemental Analysis: C, 54.72; H, 8.83; N, 19.63; O, 16.82


Specification:

Synonym: CTP-499; CTP 499; CTP499.

IUPAC/Chemical Name: (S)-1-(5-hydroxyhexyl-4,4,6,6,6-d5)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

InChi Key: NSMXQKNUPPXBRG-WHPHVCHMSA-N

InChi Code: InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m0/s1/i1D3,6D2

SMILES Code: O=C(N1CCCC([2H])([2H])[C@@H](O)C([2H])([2H])[2H])N(C)C2=C(N(C)C=N2)C1=O

Appearance: Solid powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: