Avoralstat, CAS 918407-35-9

  • Avoralstat, CAS 918407-35-9

Avoralstat, CAS 918407-35-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 918407-3918407-35-95-9
  • Stock: 837g
  • Assay: 98.23%

Avoralstat, CAS 918407-35-9

Avoralstat, CAS 918407-35-9, Stock 837g, Assay 98.23%, White powderWater 0.57%, Single Impurity 0.82%.


Avoralstat

Avoralstat, also known as BCX-4161, is a potent and orally active Kallikrein inhibitor and Bradykinin inhibitor. Avoralstat may be potentially useful for treatment for Hereditary angioedema. Avoralstat inhibits plasma kallikrein and suppresses bradykinin production. Bradykinin is the mediator of acute swelling attacks in HAE patients.


Product Details:

Name: Avoralstat

CAS#: 918407-35-9

Chemical Formula: C28H27N5O5

Exact Mass: 513.2012

Molecular Weight: 513.554

Elemental Analysis: C, 65.49; H, 5.30; N, 13.64; O, 15.58


Specification:

Synonym: BCX-4161; BCX 4161; BCX4161; Avoralstat

IUPAC/Chemical Name: 3-{2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl}-6-[(cyclopropylmethyl)carbamoyl]pyridine-2-carboxylic acid

InChi Key: TUWMKPVJGGWGNL-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H27N5O5/c1-3-16-12-21(26(34)32-18-8-6-17(7-9-18)25(29)30)20(13-23(16)38-2)19-10-11-22(33-24(19)28(36)37)27(35)31-14-15-4-5-15/h3,6-13,15H,1,4-5,14H2,2H3,(H3,29,30)(H,31,35)(H,32,34)(H,36,37)

SMILES Code: O=C(C1=NC(C(NCC2CC2)=O)=CC=C1C3=CC(OC)=C(C=C)C=C3C(NC4=CC=C(C(N)=N)C=C4)=O)O

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: