AZD8931,Sapitinib, CAS 848942-61-0

  • AZD8931,Sapitinib, CAS 848942-61-0

AZD8931,Sapitinib, CAS 848942-61-0
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 848942-61-0
  • Stock: 556g
  • Assay: 98.91%

AZD8931,Sapitinib, CAS 848942-61-0

AZD8931,Sapitinib, CAS 848942-61-0, Stock 556g, Assay 98.91%, White powderWater 0.24%, Single Impurity 0.19%.


Sapitinib, also known as AZD-8931, is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. erbB kinase inhibitor AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization.

Product Details:

Name: Sapitinib free base

CAS#: 848942-61-0 (free bade)

Chemical Formula: C23H25ClFN5O3

Exact Mass: 473.163

Molecular Weight: 473.93

Elemental Analysis: C, 58.29; H, 5.32; Cl, 7.48; F, 4.01; N, 14.78; O, 10.13


Synonym: AZD8931; AZD8931; AZD 8931; Sapitinib

IUPAC/Chemical Name: 2-(4-((4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)piperidin-1-yl)-N-methylacetamide


InChi Code: InChI=1S/C23H25ClFN5O3/c1-26-21(31)12-30-8-6-14(7-9-30)33-20-10-15-18(11-19(20)32-2)27-13-28-23(15)29-17-5-3-4-16(24)22(17)25/h3-5,10-11,13-14H,6-9,12H2,1-2H3,(H,26,31)(H,27,28,29)


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001