Nelotanserin, CAS 839713-36-9

  • Nelotanserin, CAS 839713-36-9

Nelotanserin, CAS 839713-36-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 839713-36-9
  • Stock: 1.86kg
  • Assay: 98.75%

Nelotanserin, CAS 839713-36-9

Nelotanserin, CAS 839713-36-9Stock 1864g, Assay 98.75%, White powderWater 0.34%, Single Impurity 0.64%.


Nelotanserin

Nelotanserin, also known as APD125, is a potent and selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia. Nelotanserin has low nanomolar potency on the 5-HT(2A) receptor with at least 30- and 5000-fold selectivity compared with 5-HT(2C) and 5-HT(2B) receptors, respectively. Nelotanserin produced statistically significant improvements in objective parameters of sleep maintenance and sleep consolidation and was well tolerated in adults with primary chronic insomnia.


Product Details:

Name: Nelotanserin

CAS#: 839713-36-9

Chemical Formula: C18H15BrF2N4O2

Exact Mass: 436.0346

Molecular Weight: 437.24

Elemental Analysis: C, 49.45; H, 3.46; Br, 18.27; F, 8.69; N, 12.81; O, 7.32


Specification:

Synonym: APD125; APD-125; APD 125; Nelotanserin

IUPAC/Chemical Name: 1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl)-3-(2,4-difluorophenyl)urea

InChi Key: COSPVUFTLGQDQL-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H15BrF2N4O2/c1-25-17(13(19)9-22-25)12-8-11(4-6-16(12)27-2)23-18(26)24-15-5-3-10(20)7-14(15)21/h3-9H,1-2H3,(H2,23,24,26)

SMILES Code: O=C(NC1=CC=C(F)C=C1F)NC2=CC=C(OC)C(C3=C(Br)C=NN3C)=C2

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: