Abexinostat, CAS 783355-60-2

  • Abexinostat, CAS 783355-60-2

Abexinostat, CAS 783355-60-2
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 783355-60-2
  • Stock: 1.07kg
  • Assay: 98.67%

Abexinostat, CAS 783355-60-2

Abexinostat, CAS 783355-60-2, Stock 1069g, Assay 98.67%, White powder, Water 0.41%, Single Impurity 0.78%.


Abexinostat, also known as PCI-24781 or CRA-024781, is novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. Abexinostat inhibits several isoforms of HDAC, resulting in an accumulation of highly acetylated histones, followed by the induction of chromatin remodeling; the selective transcription of tumor suppressor genes; and the tumor suppressor protein-mediated inhibition of tumor cell division and induction of tumor cell apoptosis.

Product Details:

Name: Abexinostat

CAS#: 783355-60-2 (free base)

Chemical Formula: C21H23N3O5

Exact Mass: 397.16377

Molecular Weight: 397.42

Elemental Analysis: C, 63.46; H, 5.83; N, 10.57; O, 20.13


Synonym: CRA-024781; CRA 024781; CRA024781; PCI24781; PCI-24781; PCI 24781; Abexinostat.

IUPAC/Chemical Name: 3-(dimethylaminomethyl)-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide


InChi Code: InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)


Appearance: White powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001