CAS 74141-12-1 | ALTR-003 : Altropane
(World's Largest Pharmaceutical Supplier)

Abstract:

CAS 74141-12-1, also known as 2-(4-(2-hydroxy-3-isopropylaminopropoxy)phenyl)acetamide, is a chemical compound with a molecular weight of 292.36 g/mol. It is commonly used in the pharmaceutical industry as a beta-blocker to treat hypertension, angina pectoris, and arrhythmia. In this article, we will explore the chemical properties and uses of CAS 74141-12-1.

1. Chemical Properties:

CAS 74141-12-1 is a white to off-white crystalline powder. It is soluble in water and methanol, slightly soluble in ethanol, and practically insoluble in ether and chloroform. Its melting point is between 120°C to 125°C. The compound has a pKa of 9.3 and a logP value of 1.3.

2. Synthesis:

CAS 74141-12-1 can be synthesized through a multi-step process starting with the reaction of 4-bromo-2-nitrophenol and isopropylamine to produce 4-(2-nitro-4-isopropoxyphenyl)amine. The resulting compound is then reacted with 2-(chloroacetyl)benzoic acid to form the desired product.

3. Uses:

CAS 74141-12-1 is primarily used as a beta-blocker in the pharmaceutical industry. It works by blocking the effects of adrenaline on the heart and blood vessels, resulting in a decrease in blood pressure and heart rate. It is commonly used to treat hypertension, angina pectoris, and arrhythmia. It has also been studied for its potential use in the treatment of migraines and anxiety disorders.

4. Safety:

CAS 74141-12-1 is generally considered safe when used as directed by a healthcare professional. However, like all medications, it may cause side effects such as dizziness, fatigue, and nausea. It should not be used in patients with a history of asthma, heart failure, or severe bradycardia.

In conclusion, CAS 74141-12-1 is a chemical compound used primarily as a beta-blocker in the pharmaceutical industry. Its chemical properties and uses make it an important component in the treatment of hypertension, angina pectoris, and arrhythmia. While it is generally considered safe, it should only be used under the guidance of a healthcare professional.