Intepirdine(SB742457) , CAS 607742-69-8

Intepirdine(SB742457) , CAS 607742-69-8, Stock 809g, Assay 98.64%, White powder, Water 0.44%, Single Impurity 0.31%.

SB-742457

Intepirdine, also known as SB-742457 and RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.

Product Details:

Name: Intepirdine

CAS#: 607742-69-8

Chemical Formula: C19H19N3O2S

Exact Mass: 353.1198

Molecular Weight: 353.44

Elemental Analysis: C, 64.57; H, 5.42; N, 11.89; O, 9.05; S, 9.07

Specification:

Synonym: SB742457; SB 742457; SB-742457; RVT-101; RVT 101; RVT101. intepirdine.

IUPAC/Chemical Name: 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline

InChi Key: JJZFWROHYSMCMU-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2

SMILES Code: O=S(C1=CC2=CC=CC(N3CCNCC3)=C2N=C1)(C4=CC=CC=C4)=O

Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: