Ethacrynic acid, CAS 58-54-8

  • Ethacrynic acid, CAS 58-54-8

Ethacrynic acid, CAS 58-54-8
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 58-54-8
  • Stock: 852g
  • Assay: 98.52%

Ethacrynic acid, CAS 58-54-8

Ethacrynic acid, CAS 58-54-8Stock 852g, Assay 98.52%, White powderWater 0.24%, Single Impurity 0.32%.

Ethacrynic acid

Etharcrynic Acid is a compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. Ethacrynic Acid is an unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.

Product Details:

Name: Ethacrynic acid

CAS#: 58-54-8 (free acid)

Chemical Formula: C13H12Cl2O4

Exact Mass: 302.01126

Molecular Weight: 303.14

Elemental Analysis: C, 51.51; H, 3.99; Cl, 23.39; O, 21.11


Related CAS #: 6500-81-8 (sodium)   58-54-8 (free acid)    

Synonym: Ethacrynic acid; Etacrinic acid; Hydromedin; Crinuryl; Mingit;MK-595; NSC 624008; NSC 85791; Otacril Reomax; Taladren

IUPAC/Chemical Name: 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid


InChi Code: InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)

SMILES Code: CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001