CAS 5408-04-8 | BASI-002 : Basimglurant Sulfate
(World's Largest Pharmaceutical Supplier)

Introduction

CAS 5408-04-8 is a chemical compound with the molecular formula C6H12N2O4. It is also known as 2,5-Dioxopyrrolidin-1-yl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside. This compound is commonly used in various fields due to its unique chemical properties.

Chemical Properties

CAS 5408-04-8 is a white to off-white crystalline powder that is soluble in water, ethanol, and methanol. It has a melting point of 153-155°C and a boiling point of 467.3°C at 760 mmHg. This compound is stable under normal conditions and does not react with most common chemicals.

Physical Properties

CAS 5408-04-8 has a molecular weight of 212.17 g/mol and a density of 1.5 g/cm³. It is a hygroscopic material that absorbs moisture from the air. When exposed to heat, it decomposes and emits toxic fumes of nitrogen oxides.

Synthesis

CAS 5408-04-8 can be synthesized by reacting glucopyranosyl bromide with pyrrolidine-2,5-dione in the presence of a base. The resulting product is then acetylated to form the final compound.

Applications

CAS 5408-04-8 has various applications in the pharmaceutical and chemical industries. It is used as a reagent in organic synthesis, particularly in the production of glycosides. This compound is also used as a building block for the synthesis of other compounds, such as pyrrolidines and piperidines. In addition, it is used as a chiral auxiliary in asymmetric synthesis.

Toxicity

CAS 5408-04-8 is considered a hazardous material and should be handled with care. It is classified as a toxic substance and can cause skin and eye irritation. Inhaling its vapors can cause respiratory problems, and ingesting it can lead to gastrointestinal distress.

Conclusion

CAS 5408-04-8 is a versatile chemical compound that has a range of applications in various industries. Its unique chemical properties make it a valuable reagent in organic synthesis and a building block for the production of other compounds. However, it should be handled with care due to its toxicity.