CAS 319460-85-0: Axitinib

  • CAS 319460-85-0: Axitinib

CAS 319460-85-0: Axitinib
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 319460-85-0
  • Stock: 639g
  • Assay: 98.59%

Axitinib, CAS 319460-85-0

Axitinib, CAS 319460-85-0, Stock 639g, Assay 98.59%, White powderWater 0.67%, Single Impurity 0.18%.


Axitinib, also known as AG013736, is an orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect. A xitinib has received FDA (27 January 2012), EMA (13 September 2012), MHRA (3 September 2012) and TGA (26 July 2012) approval for use as a treatment for renal cell carcinoma.

Product Details:

Name: Axitinib

CAS#: 319460-85-0

Chemical Formula: C22H18N4OS

Exact Mass: 386.12013

Molecular Weight: 386.47

Elemental Analysis: C, 68.37; H, 4.69; N, 14.50; O, 4.14; S, 8.30


Synonym: AG013736; AG 013736; AG-013736; Axitinib; Brand name: Inlyta.

IUPAC/Chemical Name: (E)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide


InChi Code: InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001