IU1, CAS 314245-33-5

  • IU1, CAS 314245-33-5

IU1, CAS 314245-33-5
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 314245-33-5
  • Stock: 920g
  • Assay: 98.74%

IU1, CAS 314245-33-5

IU1, CAS 314245-33-5Stock 920g, Assay 98.74%, White powderWater 0.21%, Single Impurity 0.3%.


IU1 is a selective USP14 inhibitor. IU1 prevents ventilator-induced lung injury in rats. IU1 inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 μM). IU1 stimulates proteasome activity and substrate degradation. USP14 removes the ubiquitin chain of I-κB, therefore inducing I-κB degradation and increasing cytokine release.

Product Details:

Name: IU1

CAS#: 314245-33-5

Chemical Formula: 18H21FN2O

Exact Mass: 300.16379

Molecular Weight: 300.37

Elemental Analysis: C, 71.98; H, 7.05; F, 6.32; N, 9.33; O, 5.33


Synonym: IU1; IU-1; IU 1

IUPAC/Chemical Name: 1-(1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethan-1-one


InChi Code: InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3


Appearance: white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001