VX-548, CAS 2649467-58-1

VX-548, CAS 2649467-58-1, Stock426g, Assay 98.39%, White powder, Water 0.15%, Single Impurity 0.19%.

VX-548

VX-548(Suzetrigine)  is a SCN10A blocker. The SCN10A is associated with the onset of pain due to peripheral neuropathy. Suzetrigine functions as an analgesic.

Product Details:

Name: Suzetrigine

CAS#: 2649467-58-1

Chemical Formula: C21H20F5N3O4

Exact Mass: 473.14

Molecular Weight: 473.400

Elemental Analysis: C, 53.28; H, 4.26; F, 20.07; N, 8.88; O, 13.52

Specification:

Synonym: Suzetrigine; VX-548; VX548; VX 548

IUPAC/Chemical Name: 4-[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2- carboxamido]pyridine-2-carboxamide

InChi Key: XSQUJFKRXZMOKA-PAFIKIDNSA-N

InChi Code: InChI=1S/C21H20F5N3O4/c1-9-14(11-4-5-12(22)15(23)16(11)32-3)17(33-20(9,2)21(24,25)26)19(31)29-10-6-7-28-13(8-10)18(27)30/h4-9,14,17H,1-3H3,(H2,27,30)(H,28,29,31)/t9-,14-,17+,20+/m0/s1

SMILES Code: O=C(C1=NC=CC(NC([C@@H]2O[C@](C(F)(F)F)(C)[C@@H](C)[C@H]2C3=CC=C(F)C(F)=C3OC)=O)=C1)N

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Shelf Life: >2 years if stored properly

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001