2169919-21-3: SNDX-5613

2169919-21-3, SNDX-5613, Stock 170g, Assay 98.39%, Yellow to light yellow powder.

SNDX-5613

Revumenib, also known as SNDX-5613, is a potent and specific Menin-MLL inhibitor. It can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).

Product Details:

Name: Revumenib

CAS#: 2169919-21-3 (free base)

Chemical Formula: C32H47FN6O4S

Exact Mass: 630.34

Molecular Weight: 630.820

Elemental Analysis: C, 60.93; H, 7.51; F, 3.01; N, 13.32; O, 10.14; S, 5.08

Specification:

Related CAS #: 2761046-45-9 (citrate)   2169919-21-3 (free base)  

Synonym: SNDX-5613; SNDX 5613; SNDX5613; Revumenib;

IUPAC/Chemical Name: N-ethyl-2-((4-(7-(((1r,4r)-4-(ethylsulfonamido)cyclohexyl)methyl)-2,7-diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)-5-fluoro-N-isopropylbenzamide

InChi Key: FRVSRBKUQZKTOW-YOCNBXQISA-N

InChi Code: InChI=1S/C32H47FN6O4S/c1-5-39(23(3)4)31(40)27-17-25(33)9-12-28(27)43-29-18-34-22-35-30(29)38-20-32(21-38)13-15-37(16-14-32)19-24-7-10-26(11-8-24)36-44(41,42)6-2/h9,12,17-18,22-24,26,36H,5-8,10-11,13-16,19-21H2,1-4H3/t24-,26-

SMILES Code: O=C(C1=CC(F)=CC=C1OC2=CN=CN=C2N3CC4(C3)CCN(CC4)C[C@H]5CC[C@@H](CC5)NS(=O)(CC)=O)N(C(C)C)CC

Appearance: Yellow to light yellow powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO and ethanol

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: