CAS 2114339-57-8: Amcenestrant

  • CAS 2114339-57-8: Amcenestrant

CAS 2114339-57-8: Amcenestrant
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 2114339-57-8
  • Stock: 139g
  • Assay: 99.76%

Amcenestrant, CAS 2114339-57-8

Amcenestrant, CAS 2114339-57-8, Stock 139g, Assay 99.76%, White powderEOS is one of TOP GMP manufacturer


Amcenestrant

Amcenestrant, also known as SAR439859, is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells


Product Details:

Name: Amcenestrant
CAS#: 2114339-57-8
Chemical Formula: C31H30Cl2FNO3
Exact Mass: 553.1587
Molecular Weight: 554.4834
Elemental Analysis: C, 67.15; H, 5.45; Cl, 12.79; F, 3.43; N, 2.53; O, 8.66


Specification:

Synonym: Amcenestrant, SAR439859; SAR-439859; SAR 439859;
IUPAC/Chemical Name: 6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acid
InChi Key: KISZAGQTIXIVAR-VWLOTQADSA-N
InChi Code: InChI=1S/C31H30Cl2FNO3/c32-23-8-12-27(29(33)18-23)28-4-1-3-21-17-22(31(36)37)7-11-26(21)30(28)20-5-9-24(10-6-20)38-25-13-16-35(19-25)15-2-14-34/h5-12,17-18,25H,1-4,13-16,19H2,(H,36,37)/t25-/m0/s1
SMILES Code:   O=C(C1=CC=C2C(CCCC(C3=CC=C(Cl)C=C3Cl)=C2C4=CC=C(O[C@@H]5CN(CCCF)CC5)C=C4)=C1)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO


Certification:

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