CAS 1953133-47-5: Giredestrant (GDC-9545)
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- CAS Number: 1953133-47-5
- Stock: 322g
- Assay: 99.29%
Giredestrant (GDC-9545): CAS 1953133-47-5
Giredestrant (GDC-9545): CAS 1953133-47-5, Stock 322g, Assay 99.29%, White to off-white powder, EOS is one of TOP GMP manufacturer
Giredestrant (GDC-9545)
Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.
Product Details:
Name: Giredestrant
CAS#: 1953133-47-5 (free base)
Chemical Formula: C27H31F5N4O
Exact Mass: 522.2418
Molecular Weight: 522.564
Elemental Analysis: C, 62.06; H, 5.98; F, 18.18; N, 10.72; O, 3.06
CAS#: 1953133-47-5 (free base)
Chemical Formula: C27H31F5N4O
Exact Mass: 522.2418
Molecular Weight: 522.564
Elemental Analysis: C, 62.06; H, 5.98; F, 18.18; N, 10.72; O, 3.06
Specification:
Synonym: GDC-9545; GDC9545; GDC 9545; RG6171; RG-6171; RG 6171; Giredestrant;
IUPAC/Chemical Name: 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol
InChi Key: GQCXHIKRWBIQMD-AKJBCIBTSA-N
InChi Code: InChI=1S/C27H31F5N4O/c1-16-9-20-19-5-2-3-6-23(19)34-25(20)26(36(16)14-27(31,32)15-37)24-21(29)10-17(11-22(24)30)33-18-12-35(13-18)8-4-7-28/h2-3,5-6,10-11,16,18,26,33-34,37H,4,7-9,12-15H2,1H3/t16-,26-/m1/s1
SMILES Code: C[C@@H]1CC(C2=C(N3)C=CC=C2)=C3[C@@H](C4=C(C=C(C=C4F)NC5CN(C5)CCCF)F)N1CC(CO)(F)F
Appearance: powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
HS Tariff Code: 2934.99.9001
IUPAC/Chemical Name: 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol
InChi Key: GQCXHIKRWBIQMD-AKJBCIBTSA-N
InChi Code: InChI=1S/C27H31F5N4O/c1-16-9-20-19-5-2-3-6-23(19)34-25(20)26(36(16)14-27(31,32)15-37)24-21(29)10-17(11-22(24)30)33-18-12-35(13-18)8-4-7-28/h2-3,5-6,10-11,16,18,26,33-34,37H,4,7-9,12-15H2,1H3/t16-,26-/m1/s1
SMILES Code: C[C@@H]1CC(C2=C(N3)C=CC=C2)=C3[C@@H](C4=C(C=C(C=C4F)NC5CN(C5)CCCF)F)N1CC(CO)(F)F
Appearance: powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
HS Tariff Code: 2934.99.9001
Certification:
