1845753-81-2: AZD2716

1845753-81-2, AZD2716, Stock 6g, Assay 98.6%, White to off-white powder.

AZD2716

AZD2716 is an investigational small-molecule drug developed by AstraZeneca. It is a selective BET (bromodomain and extraterminal domain) protein inhibitor, particularly targeting BRD4, which plays a key role in regulating gene transcription linked to inflammation and cancer. AZD2716 is under evaluation for its anti-inflammatory and anti-fibrotic properties, especially in diseases such as chronic obstructive pulmonary disease (COPD) and fibrosis-related conditions. 

Product Details:

Name: AZD2716

CAS#: 1845753-81-2

Chemical Formula: C24H23NO3

Exact Mass: 373.1678

Molecular Weight: 373.45

Elemental Analysis: C, 77.19; H, 6.21; N, 3.75; O, 12.85

Specification:

Synonym: AZD2716; AZD-2716; AZD 2716.

IUPAC/Chemical Name: (R)-3-(5'-benzyl-2'-carbamoyl-[1,1'-biphenyl]-3-yl)-2-methylpropanoic acid

InChi Key: PXRCDPVYRPKGGI-MRXNPFEDSA-N

InChi Code: InChI=1S/C24H23NO3/c1-16(24(27)28)12-18-8-5-9-20(14-18)22-15-19(10-11-21(22)23(25)26)13-17-6-3-2-4-7-17/h2-11,14-16H,12-13H2,1H3,(H2,25,26)(H,27,28)/t16-/m1/s1

SMILES Code: O=C(N)C1=C(C2=CC=CC(C[C@@H](C)C(O)=O)=C2)C=C(CC3=CC=CC=C3)C=C1

Appearance: White to off-white powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification:

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