Blu-285, CAS 1703793-34-3

  • Blu-285, CAS 1703793-34-3

Blu-285, CAS 1703793-34-3
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1703793-34-3
  • Stock: 624g
  • Assay: 98.36%

Blu-285, CAS 1703793-34-3

Blu-285, CAS 1703793-34-3Stock 624g, Assay 98.36%, White powderWater 0.58%, Single Impurity 0.26%.


Avapritinib, also known as BlU-285, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint.

Product Details:

Name: Avapritinib

CAS#: 1703793-34-3

Chemical Formula: C26H27FN10

Exact Mass: 498.2404

Molecular Weight: 498.5704

Elemental Analysis: C, 62.64; H, 5.46; F, 3.81; N, 28.09


Synonym: BLU-285; BLU 285; BLU285, Avapritinib

IUPAC/Chemical Name: (S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)piperazin-1-yl)pyrimidin-5-yl)ethan-1-amine


InChi Code: InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1

SMILES Code: CN1N=CC(C2=CN3C(C(N4CCN(C5=NC=C([C@@](C)(N)C6=CC=C(F)C=C6)C=N5)CC4)=NC=N3)=C2)=C1

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001