ONC206, CAS 1638178-87-6
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ONC206, CAS 1638178-87-6

ONC206, CAS 1638178-87-6, Stock 1244g, Assay 98.52%, White powder, Water 0.24%, Single Impurity 0.49%.

ONC206

ONC206 is a chemical analogue of ONC201. ONC206 is a benzyl-flurobenzyl imipridone that has highly potent activity in preclinical models of difficult-to-treat neuroendocrine tumors and sarcomas. ONC206 acts as a selective antagonist of DRD2 at nanomolar concentrations and has broad-spectrum anti-tumor activity. ONC206 may address tumor types where the properties of ONC201 do not permit for complete therapeutic engagement in vivo.

Product Details:

Name: ONC206

CAS#: 1638178-87-6

Chemical Formula: C23H22F2N4O

Exact Mass: 408.176

Molecular Weight: 408.4528

Elemental Analysis: C, 67.63; H, 5.43; F, 9.30; N, 13.72; O, 3.92

Specification:

Synonym: ONC206; ONC-206; ONC 206.

IUPAC/Chemical Name: 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one

InChi Key: ITMGVSSHWMTJRR-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H22F2N4O/c24-18-7-6-17(20(25)12-18)14-29-22(30)19-15-27(13-16-4-2-1-3-5-16)10-8-21(19)28-11-9-26-23(28)29/h1-7,12H,8-11,13-15H2

SMILES Code: FC1=CC(F)=CC=C1CN2C(C(C3)=C(N4CCN=C42)CCN3CC5=CC=CC=C5)=O

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: