Seralutinibm,CAS1619931-27-9

Seralutinibm,CAS1619931-27-9
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  • CAS Number: 1619931-27-9
  • Stock: 56g
  • Assay: 98.20%

Seralutinibm,CAS1619931-27-9

Seralutinibm,CAS1619931-27-9Stock 56.6g, Assay 98.20%, Solid powderWater 0.19%, Single Impurity 0.16%.


Seralutinibm

Adagrasib, also known as MRTX849, is a potent, highly selective, oral available KRAS G12C inhibitor. MRTX849 maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. MRTX849 exhibited significantly improved half-life and penetration into the tumor, shutting down KRAS signaling for the entire dosing interval, and showing a higher degree of antitumor activity than previous KRAS mutant-selective inhibitors.


Product Details:

Name: Seralutinib

CAS#: 1619931-27-9

Chemical Formula: C27H27N5O3

Exact Mass: 469.2114

Molecular Weight: 469.545

Elemental Analysis: C, 69.07; H, 5.80; N, 14.92; O, 10.22


Specification:

Synonym: Seralutinib; PK-10571; PK10571; PK 10571; GB002; GB-002; GB 002;

IUPAC/Chemical Name: N-{3-[(1S)-1-{[6-(3,4-dimethoxyphenyl)pyrazin-2- yl]amino}ethyl]phenyl}-5-methylpyridine-3-carboxamide

InChi Key: JHJNPOSPVGRIAN-SFHVURJKSA-N

InChi Code: InChI=1S/C27H27N5O3/c1-17-10-21(14-28-13-17)27(33)31-22-7-5-6-19(11-22)18(2)30-26-16-29-15-23(32-26)20-8-9-24(34-3)25(12-20)35-4/h5-16,18H,1-4H3,(H,30,32)(H,31,33)/t18-/m0/s1

SMILES Code: O=C(C1=CC(C)=CN=C1)NC2=CC=CC([C@@H](NC3=NC(C4=CC=C(OC)C(OC)=C4)=CN=C3)C)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certification: