Seralutinibm,CAS1619931-27-9
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- CAS Number: 1619931-27-9
- Stock: 56g
- Assay: 98.20%
Seralutinibm,CAS1619931-27-9
Seralutinibm,CAS1619931-27-9, Stock 56.6g, Assay 98.20%, Solid powder, Water 0.19%, Single Impurity 0.16%.
Seralutinibm
Adagrasib, also known as MRTX849, is a potent, highly selective, oral available KRAS G12C inhibitor. MRTX849 maximizes inhibition by irreversibly locking the KRAS molecule in its inactive state, thereby preventing tumor cell growth which results in tumor cell death. MRTX849 exhibited significantly improved half-life and penetration into the tumor, shutting down KRAS signaling for the entire dosing interval, and showing a higher degree of antitumor activity than previous KRAS mutant-selective inhibitors.
Product Details:
Name: Seralutinib
CAS#: 1619931-27-9
Chemical Formula: C27H27N5O3
Exact Mass: 469.2114
Molecular Weight: 469.545
Elemental Analysis: C, 69.07; H, 5.80; N, 14.92; O, 10.22
Specification:
Synonym: Seralutinib; PK-10571; PK10571; PK 10571; GB002; GB-002; GB 002;
IUPAC/Chemical Name: N-{3-[(1S)-1-{[6-(3,4-dimethoxyphenyl)pyrazin-2- yl]amino}ethyl]phenyl}-5-methylpyridine-3-carboxamide
InChi Key: JHJNPOSPVGRIAN-SFHVURJKSA-N
InChi Code: InChI=1S/C27H27N5O3/c1-17-10-21(14-28-13-17)27(33)31-22-7-5-6-19(11-22)18(2)30-26-16-29-15-23(32-26)20-8-9-24(34-3)25(12-20)35-4/h5-16,18H,1-4H3,(H,30,32)(H,31,33)/t18-/m0/s1
SMILES Code: O=C(C1=CC(C)=CN=C1)NC2=CC=CC([C@@H](NC3=NC(C4=CC=C(OC)C(OC)=C4)=CN=C3)C)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001