CAS 1607799-13-2: Bremelanotide acetate
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Bremelanotide acetate, CAS 160743-62-4:

Bremelanotide acetate, CAS 1607799-13-2, Stock 215g, Assay 98.41%, White powder, Water 0.21%, Single Impurity 0.14%.

Bremelanotide acetate

Bremelanotide is a melanocortin receptor (MCR) agonist that nonselectively activates several receptor subtypes with the following order of potency: MC1R, MC4R, MC3R, MC5R, MC2R. At therapeutic dose levels, binding to MC1R and MC4R is most relevant. Neurons expressing MC4R are present in many areas of the central nervous system (CNS). The mechanism by which VYLEESI improves HSDD in women is unknown. The MC1R is expressed on melanocytes; binding at this receptor leads to melanin expression and increased pigmentation. Bremelanotide was approved in 6/21/2018 To treat hypoactive sexual desire disorder in premenopausal women.

Product Details:

Name: Bremelanotide acetate

CAS#: 1607799-13-2 (acetate)

Chemical Formula: C52H72N14O12

Exact Mass:

Molecular Weight: 1085.234

Elemental Analysis: C, 57.55; H, 6.69; N, 18.07; O, 17.69

Specification:

Related CAS #: 1607799-13-2 (acetate)   189691-06-3 (free base)    

Synonym: Bremelanotide acetate; Bremelanotide; PT 141 acetate; PT-141 acetate; PT141 acetate;

IUPAC/Chemical Name: (3S,6S,9R,12S,15S,23S)-12-((1H-imidazol-5-yl)methyl)-3-((1H-indol-3-yl)methyl)-15-((S)-2-acetamidohexanamido)-9-benzyl-6-(3-guanidinopropyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxylic acid compound with acetic acid (1:1)

InChi Key: MAYUSRUHXFWITM-GBRHMYBBSA-N

InChi Code: InChI=1S/C50H68N14O10.C2H4O2/c1-3-4-16-35(58-29(2)65)43(67)64-41-25-42(66)54-20-11-10-18-37(49(73)74)60-46(70)39(23-31-26-56-34-17-9-8-15-33(31)34)62-44(68)36(19-12-21-55-50(51)52)59-45(69)38(22-30-13-6-5-7-14-30)61-47(71)40(63-48(41)72)24-32-27-53-28-57-32;1-2(3)4/h5-9,13-15,17,26-28,35-41,56H,3-4,10-12,16,18-25H2,1-2H3,(H,53,57)(H,54,66)(H,58,65)(H,59,69)(H,60,70)(H,61,71)(H,62,68)(H,63,72)(H,64,67)(H,73,74)(H4,51,52,55);1H3,(H,3,4)/t35-,36-,37-,38+,39-,40-,41-;/m0./s1

SMILES Code: O=C([C@@H](NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CCCNC(N)=N)NC([C@@H](CC3=CC=CC=C3)NC([C@H](CC4=CN=CN4)NC([C@@H](NC([C@@H](NC(C)=O)CCCC)=O)C5)=O)=O)=O)=O)=O)CCCCNC5=O)O.CC(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certification: