CAS 1599432-08-2: NIBR-189
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- CAS Number: 1599432-08-2
- Stock: 256g
- Assay: 99.14%
NIBR-189, CAS 1599432-08-2:
NIBR-189, CAS 1599432-08-2, Stock 256g, Assay 99.14%, White powder, Water 0.19%, Single Impurity 0.17%.
NIBR-189
NIBR-189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). NIBR-189 blocks migration of a monocyte cell line called U937, suggesting a functional role of the oxysterol/EBI2 pathway in these immune cells.
Product Details:
Name: NIBR-189
CAS#: 1599432-08-2
Chemical Formula: C21H21BrN2O3
Exact Mass: 428.0736
Molecular Weight: 429.314
Elemental Analysis: C, 58.75; H, 4.93; Br, 18.61; N, 6.53; O, 11.18
Specification:
Synonym: NIBR-189; NIBR 189; NIBR189.
IUPAC/Chemical Name: (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one
InChi Key: OFHXXBRBGWUOHR-NYYWCZLTSA-N
InChi Code: InChI=1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+
SMILES Code: O=C(N1CCN(C(C2=CC=C(OC)C=C2)=O)CC1)/C=C/C3=CC=C(Br)C=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certification:
