CAS 157716-52-4: Perifosine
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- CAS Number: 157716-52-4
- Stock: 125g
- Assay: 98.43%
Perifosine, CAS 157716-52-4:
Perifosine, CAS 157716-52-4, Stock 125g, Assay 98.43%, White powder, Water 0.19%, Single Impurity 0.21%.
Perifosine
Perifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine.
Product Details:
Name: Perifosine
CAS#: 157716-52-4
Chemical Formula: C25H52NO4P
Exact Mass: 461.3634
Molecular Weight: 461.66
Elemental Analysis: C, 65.04; H, 11.35; N, 3.03; O, 13.86; P, 6.71
Specification:
Synonym: KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; Perifosine
IUPAC/Chemical Name: 1,1-dimethylpiperidin-1-ium-4-yl octadecyl phosphate.
InChi Key: SZFPYBIJACMNJV-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3
SMILES Code: O=P(OC1CC[N+](C)(C)CC1)([O-])OCCCCCCCCCCCCCCCCCC
Appearance: Solid powder
Purity: >96% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Certification:
