CAS 1575818-46-0: PRN694

CAS 1575818-46-0: PRN694
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  • CAS Number: 1575818-46-0
  • Stock: 701g
  • Assay: 98.40%

PRN694, CAS 1575818-46-0:

PRN694, CAS 1575818-46-0Stock 701g, Assay 98.4%, White powderWater 0.21%, Single Impurity 0.19%.



PRN694

PRN694 is a highly selective and potent covalent inhibitor of Tec kinases IL-2-inducible T cell kinase (ITK) and resting lymphocyte kinase (RLK). It inhibits Th1 and Th17 differentiation and cytokine production.


Product Details:

Name: PRN694

CAS#: 1575818-46-0

Chemical Formula: C28H35F2N5O2S

Exact Mass: 543.248

Molecular Weight: 543.67

Elemental Analysis: C, 61.86; H, 6.49; F, 6.99; N, 12.88; O, 5.89; S, 5.90



Specification:

Synonym: PRN694; PRN-694; PRN 694;

IUPAC/Chemical Name: 5-(Difluoromethyl)-N-[1-[[(2R)-1-(1-oxo-2-propen-1-yl)-2-pyrrolidinyl]methyl]-5-[[[(1S)-1,2,2-trimethylpropyl]amino]methyl]-1H-benzimidazol-2-yl]-2-thiophenecarboxamide

InChi Key: NXTKFBGDLDPFLB-PKOBYXMFSA-N

InChi Code: InChI=1S/C28H35F2N5O2S/c1-6-24(36)34-13-7-8-19(34)16-35-21-10-9-18(15-31-17(2)28(3,4)5)14-20(21)32-27(35)33-26(37)23-12-11-22(38-23)25(29)30/h6,9-12,14,17,19,25,31H,1,7-8,13,15-16H2,2-5H3,(H,32,33,37)/t17-,19+/m0/s1

SMILES Code: O=C(C1=CC=C(C(F)F)S1)NC2=NC3=CC(CN[C@@H](C)C(C)(C)C)=CC=C3N2C[C@@H]4N(C(C=C)=O)CCC4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001



Certification: