CAS 150727-72-3 | AVOS-001 : Avosentan
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CAS 150727-72-3 is a chemical compound with the molecular formula C21H17N3O3S. It is also known by its trade name, Sitagliptin, and is primarily used as an oral medication for the treatment of type 2 diabetes mellitus.

Chemical Properties

CAS 150727-72-3 is a white to off-white powder that is soluble in water and methanol but insoluble in acetone and ethyl acetate. It has a melting point of 182-183°C and a molecular weight of 407.44 g/mol.

Usage

CAS 150727-72-3 is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which means it works by increasing the levels of incretin hormones in the body. These hormones stimulate the release of insulin from the pancreas and decrease the amount of glucose produced by the liver, thereby reducing blood sugar levels.

Sitagliptin is used in combination with diet and exercise to control high blood sugar levels in patients with type 2 diabetes mellitus. It is also sometimes used in combination with other medications such as metformin or pioglitazone.

Side Effects

Like all medications, Sitagliptin may cause side effects in some patients. The most common side effects include headache, nausea, and diarrhea. In rare cases, it may cause severe allergic reactions or pancreatitis.

Conclusion

CAS 150727-72-3 is an important medication for the treatment of type 2 diabetes mellitus. As with all medications, it is important to use it as directed by a healthcare professional and to be aware of any potential side effects.