Copanlisib HCI, CAS 1402152-13-9

  • Copanlisib HCI, CAS 1402152-13-9

Copanlisib HCI, CAS 1402152-13-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1402152-13-9
  • Stock: 837g
  • Assay: 98.63%

Copanlisib HCI, CAS 1402152-13-9

Copanlisib HCI, CAS1402152-13-9, Stock 837g, Assay 98.63%, White powder, Water 0.35%, Single Impurity 0.76%.


Copanlisib HCI

Copanlisib also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) inhibitor. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Copanlisib was approved for the treatment of adult patients experiencing relapsed follicular lymphoma who have received at least two prior systemic therapies.


Product Details:

Name: Copanlisib HCl

CAS#: 1402152-13-9 (HCl)

Chemical Formula: C23H30Cl2N8O4

Exact Mass:

Molecular Weight: 553.445

Elemental Analysis: C, 49.92; H, 5.46; Cl, 12.81; N, 20.25; O, 11.56


Specification:

Synonym: Copanlisib HCl; Copanlisib dihydrochloride; BAY 80-6946; BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946; Copanlisib; trade name Aliqopa.

IUPAC/Chemical Name: 5-Pyrimidinecarboxamide, 2-amino-N-(2,3-dihydro-7-methoxy-8-(3-(4-morpholinyl)propoxy)imidazo(1,2-C)quinazolin-5-yl)-, hydrochloride (1:2)

InChi Key: STGQPVQAAFJJFX-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H28N8O4.2ClH/c1-33-19-17(35-10-2-6-30-8-11-34-12-9-30)4-3-16-18(19)28-23(31-7-5-25-20(16)31)29-21(32)15-13-26-22(24)27-14-15;;/h3-4,13-14H,2,5-12H2,1H3,(H2,24,26,27)(H,28,29,32);2*1H

SMILES Code: O=C(C1=CN=C(N)N=C1)NC2=NC3=C(C=CC(OCCCN4CCOCC4)=C3OC)C5=NCCN25.[H]Cl.[H]Cl

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


Certifications: