Vericiguat, CAS 1350653-20-1
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- CAS Number: 1350653-20-1
- Stock: 726g
- Assay: 98.53%
Vericiguat, CAS 1350653-20-1
Vericiguat, CAS 1350653-20-1, Stock 726g, Assay 98.53%, White powder, Water 0.67%, Single Impurity 0.2%.
Vericiguat
Vericiguat, also known as BAY1021189 or BAY10-21189, is a potent and orally active sGC stimulator (Soluble Guanylate Cyclase Stimulator). Direct stimulation of soluble guanylate cyclase (sGC) is emerging as a potential new approach for the treatment of renal disorders. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is implicated in the pathogenesis of chronic kidney disease (CKD).
Product Details:
Name: Vericiguat
CAS#: 1350653-20-1
Chemical Formula: C19H16F2N8O2
Exact Mass: 426.1364
Molecular Weight: 426.39
Elemental Analysis: C, 53.52; H, 3.78; F, 8.91; N, 26.28; O, 7.50
Specification:
Synonym: BAY1021189; BAY 1021189; BAY-1021189; BAY10-21189; BAY-10-21189; BAY 10-21189; Vericiguat.
IUPAC/Chemical Name: methyl (4,6-diamino-2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
InChi Key: QZFHIXARHDBPBY-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H16F2N8O2/c1-31-19(30)25-14-15(22)26-17(27-16(14)23)13-11-6-10(20)7-24-18(11)29(28-13)8-9-4-2-3-5-12(9)21/h2-7H,8H2,1H3,(H,25,30)(H4,22,23,26,27)
SMILES Code: O=C(OC)NC1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=NC=C(F)C=C42)N=C1N
Appearance: White powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001