CAS 1346242-81-6 : Erdafitinib ( JNJ-42756493 )

  • CAS 1346242-81-6 : Erdafitinib ( JNJ-42756493 )

CAS 1346242-81-6 : Erdafitinib ( JNJ-42756493 )
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1346242-81-6
  • Stock: 210g
  • Assay: 99.64%

Erdafitinib(JNJ-42756493), CAS 1346242-81-6

Erdafitinib(JNJ-42756493), CAS 1346242-81-6Stock 210g, Assay 99.64%, White powderWater 0.31%, Single Impurity 0.36%.


Erdafitinib, also known as JNJ-42756493, is a potent and selective orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, JNJ-42756493 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival.

Product Details:

Name: Erdafitinib

CAS#: 1346242-81-6

Chemical Formula: C25H30N6O2

Exact Mass: 446.24302

Molecular Weight: 446.55

Elemental Analysis: C, 67.24; H, 6.77; N, 18.82; O, 7.17


Synonym: JNJ-42756493; JNJ 42756493; JNJ42756493; Erdafitinib

IUPAC/Chemical Name: N1-(3,5-dimethoxyphenyl)-N2-isopropyl-N1-(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)ethane-1,2-diamine


InChi Code: InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001