CAS 130446-90-1 | CELG-004 : Celgosivir
(World's Largest Pharmaceutical Supplier)

CAS 130446-90-1 is a chemical compound known as esomeprazole magnesium. It is a medication that belongs to the class of proton pump inhibitors (PPIs) and is primarily used in the treatment of gastroesophageal reflux disease (GERD), gastric ulcers, and other conditions related to excessive stomach acid production.

Esomeprazole magnesium is a white to slightly colored crystalline powder that is soluble in water. Its chemical formula is C34H36MgN6O6S2, and it is available in capsule or tablet form for oral administration.

One of the main uses of CAS 130446-90-1 is in the management of GERD, a condition characterized by the backward flow of stomach acid into the esophagus, causing symptoms such as heartburn, regurgitation, and difficulty swallowing. Esomeprazole magnesium works by inhibiting the enzyme H+/K+-ATPase, which is responsible for the final step of acid production in the stomach. By reducing stomach acid production, it helps alleviate symptoms and promotes healing of the esophageal lining.

Moreover, esomeprazole magnesium is effective in the treatment and prevention of gastric ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs can irritate the stomach lining and increase the risk of ulcer formation. Esomeprazole magnesium helps protect the stomach by reducing acid secretion and allowing the ulcers to heal.

Additionally, esomeprazole magnesium may be prescribed in combination with antibiotics for the eradication of Helicobacter pylori, a bacterium associated with peptic ulcers and gastritis. The PPI component of esomeprazole magnesium helps create an environment in the stomach that is less favorable for H. pylori growth, enhancing the effectiveness of antibiotic therapy.

It is important to note that esomeprazole magnesium should be used under medical supervision, and dosage adjustments may be necessary based on individual patient factors. Common side effects may include headache, diarrhea, and abdominal pain. Rare but serious side effects, such as allergic reactions and increased risk of certain infections, have been reported and should be monitored by healthcare professionals.

In conclusion, CAS 130446-90-1, or esomeprazole magnesium, is a medication used in the treatment of GERD, gastric ulcers, and related conditions. By reducing stomach acid production, it helps alleviate symptoms, promote healing, and protect the stomach lining. However, it should be used under medical supervision, and patients should be aware of potential side effects. Regular monitoring and adherence to a comprehensive treatment plan are crucial for optimal outcomes.