enarodustat(JTZ-951), CAS 1262132-81-9

  • enarodustat(JTZ-951), CAS 1262132-81-9

enarodustat(JTZ-951), CAS 1262132-81-9
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1262132-81-9
  • Stock: 894g
  • Assay: 98.74%

Enarodustat(JTZ-951), CAS 1262132-81-9

Enarodustat(JTZ-951), CAS 1262132-81-9Stock 894g, Assay 98.74%, White powderWater 0.24%, Single Impurity 0.32%.


Enarodustat, also known as JTZ-951, is a prolyl hydroxylase inhibitor. JTZ-951 (enarodustat) stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor. Enarodustat increases endogenous erythropoietin levels in the treatment of anemia associated with chronic kidney disease (CKD). JTZ-951 induces erythropoiesis without affecting VEGF function. JTZ-951 may be a new oral candidate that increases and maintains hemoglobin concentrations in renal anemia patients.

Product Details:

Name: Enarodustat

CAS#: 1262132-81-9 (free base)

Chemical Formula: C17H16N4O4

Exact Mass: 340.1172

Molecular Weight: 340.34

Elemental Analysis: C, 60.00; H, 4.74; N, 16.46; O, 18.80


Related CAS #: 1262132-81-9 (free base)   1262131-60-1 (HCl)   1262133-55-0 (disodium)    

Synonym: Enarodustat; JTZ-951; JTZ 951; JTZ951;

IUPAC/Chemical Name: N-[7-hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl]glycine


InChi Code: InChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5,8,10,22H,6-7,9H2,(H,18,25)(H,23,24)


Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001