Vonoprazan( Tak-438 ), CAS 1260141-27-2

  • Vonoprazan( Tak-438 ), CAS 1260141-27-2

Vonoprazan( Tak-438 ), CAS 1260141-27-2
(World's Largest Pharmaceutical Supplier)

  • CAS Number: 1260141-27-2
  • Stock: 909g
  • Assay: 98.57%

Vonoprazan( Tak-438 ), CAS 1260141-27-2

Vonoprazan( Tak-438 ), CAS 1260141-27-2Stock 909g, Assay 98.57%, White powderWater 0.23%, Single Impurity 0.32%.


Vonoprazan Fumarate, also known as TAK438, is a new medicine for treating acid-related diseases with a novel mechanism of action called potassium-competitive acid blockers (P-CABs) which competitively inhibits the binding of potassium ions to H+,K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells. TAKECAB provides a strong and sustained acid secretion inhibitory effect.

Product Details:

Name: Vonoprazan Fumarate

CAS#: 1260141-27-2 (fumarate)

Chemical Formula: C21H20FN3O6S

Exact Mass:

Molecular Weight: 461.46

Elemental Analysis: C, 54.66; H, 4.37; F, 4.12; N, 9.11; O, 20.80; S, 6.95


Related CAS #: 881681-00-1 (free base)   1260141-27-2 (fumarate)   1260141-27-2  

Synonym: TAK438, TAK-438, TAK 438, Vonoprazan Fumarate, Vonoprazan, Takecab

IUPAC/Chemical Name: 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate


InChi Code: InChI=1S/C17H16FN3O2S.C4H4O4/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14;5-3(6)1-2-4(7)8/h2-9,11-12,19H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

SMILES Code: CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001