MK7622, CAS 1227923-29-6
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MK7622, CAS 1227923-29-6

MK7622, CAS 1227923-29-6, Stock 866g, Assay 98.39%, White powder, Water 0.23%, Single Impurity 0.75%.

MK7622

MK-7622 is a cholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease. No studies have been published on this compound in the peer-reviewed literature or other publicly available documents. In October 2013, Merck began a Phase 2 trial in the United States to evaluate the compound's tolerability and efficacy as a symptomatic adjunct to donepezil therapy in patients with probable AD as diagnosed by two conventional diagnostic criteria, the NINCDS-ADRDA and DSM-IV.

Product Details:

Name: MK-7622

CAS#: 1227923-29-6

Chemical Formula: C25H25N3O2

Exact Mass: 399.1947

Molecular Weight: 399.494

Elemental Analysis: C, 75.16; H, 6.31; N, 10.52; O, 8.01

Specification:

Synonym: MK7622; MK 7622; MK-7622.

IUPAC/Chemical Name: 3-((1S,2S)-2-hydroxycyclohexyl)-6-((6-methylpyridin-3-yl)methyl)benzo[h]quinazolin-4(3H)-one

InChi Key: JUVQLZBJFOGEEO-GOTSBHOMSA-N

InChi Code: InChI=1S/C25H25N3O2/c1-16-10-11-17(14-26-16)12-18-13-21-24(20-7-3-2-6-19(18)20)27-15-28(25(21)30)22-8-4-5-9-23(22)29/h2-3,6-7,10-11,13-15,22-23,29H,4-5,8-9,12H2,1H3/t22-,23-/m0/s1

SMILES Code: O=C1N([C@@H]2[C@@H](O)CCCC2)C=NC3=C1C=C(CC4=CC=C(C)N=C4)C5=CC=CC=C53

Appearance: White  powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: