Mirogabalin, CAS 1138245-13-2
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Mirogabalin, CAS 1138245-13-2

Mirogabalin, CAS 1138245-13-2, Stock 1423g, Assay 98.64%, White powder, Water 0.14%, Single Impurity 0.73%.

Mirogabalin

Mirogabalin, also known as DS-5565, is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia. Mirogabalin was estimated to be 17-fold more potent than pregabalin. Mirogabalin is being developed by Daiichi Sankyo and related to drugs such as gabapentin and pregabalin. Similarly to these drugs, mirogabalin binds to the α2δ calcium channels (1 and 2), but with significantly higher potency than pregabalin. It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain.

Product Details:

Name: Mirogabalin free base

CAS#: 1138245-13-2 (free base)

Chemical Formula: C12H19NO2

Exact Mass: 209.1416

Molecular Weight: 209.289

Elemental Analysis: C, 68.87; H, 9.15; N, 6.69; O, 15.29

Specification:

Synonym: DS-5565; DS 5565; DS5565; A-2000700; Mirogabalin; Mirogabalin besylate; Mirogabalin free base.

IUPAC/Chemical Name: 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid

InChi Key: FTBQORVNHOIASH-CKYFFXLPSA-N

InChi Code: InChI=1S/C12H19NO2/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15)/t9-,10-,12-/m1/s1

SMILES Code: O=C(O)C[C@]1(CN)[C@]2([H])C=C(CC)C[C@]2([H])C1

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: