MK-2206 2HCl , CAS 1032350-13-2
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MK-2206 2HCl , CAS 1032350-13-2

MK-2206 2HCl , CAS 1032350-13-2, Stock 1352g, Assay 98.64%, White powder, Water 0.75%, Single Impurity 0.34%.

MK-2206 2HCl 

MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

Product Details:

Name: MK-2206 2HCl

CAS#: 1032350-13-2 (2HCl)

Chemical Formula: C25H25Cl2N5O

Exact Mass:

Molecular Weight: 409.48483

Elemental Analysis: C, 62.24; H, 5.22; Cl, 14.70; N, 14.52; O, 3.32

Specification:

Synonym: MK2206; MK-2206; MK 2206; MK2206 dihydrochloride; MK2206 HCl.

IUPAC/Chemical Name: 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride

InChi Key: AVWUIYMDWOYEFM-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H23N5O.2ClH/c26-25(12-4-13-25)18-9-7-17(8-10-18)22-19(16-5-2-1-3-6-16)15-20-21(27-22)11-14-30-23(20)28-29-24(30)31;;/h1-3,5-11,14-15,19,22H,4,12-13,26H2,(H,29,31);2*1H

SMILES Code: O=C1NN=C2C3=CC(C4=CC=CC=C4)C(C5=CC=C(C6(N)CCC6)C=C5)N=C3C=CN21.[H]Cl.[H]Cl

Appearance: White powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certifications: